Position: RESEARCH FELLOW

Location: University of Michigan

Lab(s): Vecchiarelli Lab
Position Description:  The Vecchiarelli Lab has an opening for a postdoctoral position in the Department of Molecular, Cellular, and Developmental Biology (MCDB).

Our lab studies the molecular mechanisms driving subcellular organization in bacteria using interdisciplinary approaches, including microbiology, cell biology, biochemistry, bioinformatics, and biophysical approaches such as cell-free reconstitution and imaging. Our current focus is understanding the ATP-driven spatial organization of protein-based complexes and condensates in bacteria. We are specifically interested in the subcellular organization of the most important organelle on Earth, the carboxysome – a carbon-fixing organelle that we study in both cyanobacteria and chemoautotrophs.

The Vecchiarelli Lab is a dynamic environment that includes trainees at all stages and is strongly committed to the development of all lab members. Professional development activities include writing/presentation skills, experimental training, networking at national conferences and opportunities to mentor junior researchers.

Candidates are encouraged to browse recent publications from the Vecchiarelli lab to determine if the research topics and skill sets are of interest. Enthusiastic applicants are encouraged to apply!
 More information click button below or visit: https://careers.umich.edu/job_detail/245300/research-fellow-vecchiarelli-lab

Position: RESEARCH LABORATORY TECH ASSOCIATE

Location: University of Michigan

Lab(s): Timothy Frankel Lab

Position Description:  Research position available for a highly motivated individual interested in cancer biology and gaining valuable lab experience. This individual will work amongst a team including medical students, residents, UM faculty, and various researchers making this a valuable opportunity for those interested in medical school. PI: Dr. Timothy Frankel, MD, https://www.uofmhealth.org/profile/3250/timothy-louis-frankel-md#research

 More information click button below or visit: https://careers.umich.edu/job_detail/245133/research-laboratory-tech-associate

Position: PROJECT MANAGER SINGLE CELL & SPATIAL TRANSCRIPTOMICS

Location: University of Michigan

Lab(s): MM BRCF Advanced Genomics Core
Position Description:  Reporting directly to the Core Director, the Research Lab Specialist Lead will function as a project manager and will work closely with the Single Cell Spatial Lab Manager, core staff, and clients to shepherd Spatialomics and Single Cell requests through the facility. The project manager must be familiar with spatial and single cell techniques (e.g 10x Genomics Visium/Xenium, Curio Biosciences, nanoString), clearly understand the role/function of each service and be highly organized with a keen sense for details in order to effectively coordinate the activities associated with spatial and single cell projects. As the primary contact for customers, this individual will coordinate, budget, and document all aspects of projects to ensure that tasks are completed, and data are delivered in a timely fashion. The primary responsibility of this individual will be to ensure the facility is providing an efficient service that meets the expectations and needs of customers and the university.

Position: RESEARCH FELLOW- NEW 

Location: University of Michigan

Lab(s): Castro/Lowenstein Laboratory- Department of Neurosurgery
Position Description: Post-Doctoral Fellowship position funded by NIH.  The successful candidate will join an exciting and productive research team focused on elucidating the molecular and physical basis of brain tumor growth, invasion and the response to novel therapeutics.  The project will study the molecular and cellular mechanisms involved in the epigenetic remodeling of the tumor immune microenvironment and how this impacts tumor progression and the response to immune mediated therapies. The project will also investigate the mechanisms that mediate genomic instability, chromatin structure and the DNA repair machinery in genetically engineered brain cancer models and samples from human patients, with the aim of uncovering novel therapeutic targets that can be readily translated into the clinical arena. The project will also investigate the mechanisms that mediate genomic instability, chromatin structure and the DNA repair machinery in genetically engineered brain cancer models and samples from human patients, with the aim of uncovering novel therapeutic targets that can be readily translated into the clinical arena. The project will also utilize state-of-the-art “omics” technologies such as Single Cell RNASeq, ChIP-Seq, ATAC-Seq, as well as advanced Bioinformatics. The project has a strong translational component focusing on the development and implementation of novel therapeutic approaches in human clinical trials for brain cancer; these include gene therapy strategies, small molecules, and nano-technologies. The lab is utilizing novel gene therapy and combination therapies and exploring ways to translate the research into novel Phase I clinical trials for brain cancer.

Position: RESEARCH FELLOW

Location: University of Michigan

Lab(s): Drs. Maureen Sartor (sartorma@umich.edu) and Dana Dolinoy (ddolinoy@umich.edu)
Position Description:  The Department of Computational Medicine and Bioinformatics (DCMB, Medical School) and the Department of Environmental Health Sciences (EHS, School of Public Health) are seeking a bioinformatics post-doctoral fellow. This position will support innovative, cross-disciplinary multi-omics and data science research, especially in the areas of epigenomics and transcriptomics (including single cell and spatial) in response to environmental exposures, and will develop novel bioinformatics algorithms in these areas. The fellow will work jointly with Drs. Maureen Sartor (Professor of DCMB and Biostatistics) and Dana Dolinoy (Professor of Environmental Health Sciences and Nutritional Sciences), with partial funding from the NIEHS-funded Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD). The specific research topics will be determined based on the expertise of the fellow and mutual interests of the fellow and mentors. Several publications as part of our team science efforts are expected. The position is expected to be over a 2-year period, with opportunities for extension or promotion. Previous post-doctoral fellows in this position have benefitted from career development opportunities, including being awarded a Center Scientist position in M-LEEaD, and have continued on to a K99/R00 grant and bioinformatics careers at Illumina Inc and Oxford University, UK.

Position: RESEARCH FELLOW

Location: University of Michigan- Pathology Department

Lab(s): Drs. Asma Nusrat and Charles Parkos
Position Description:  Opportunities for creative and motivated postdocs to participate in cutting-edge exciting research projects that investigate gut leukocyte trafficking during inflammatory diseases and mucosal wound repair. Our studies employ state-of-the-art immunology, molecular/cell biology, imaging, and multi-omics (proteomics, single-cell sequencing including spatial transcriptomics) approaches. Experimental approaches also utilize many genetically modified mice, stem cell derived organoids and human tissues.

Position: CLIN RES PROJECT MANAGER – NEW

Location: University of Michigan

Lab: The Parker Research Laboratory and home of the Epigenomic Metabolic Medicine Center 
Position Description:  seeking a skilled Research Project Manager to work closely with Dr. Steve Parker, Center Director, to provide project management support for NIH, industry, and foundation science projects. The center aims to create population-scale single cell multi-omics maps, with focus on the epigenome using cutting edge computational approaches. The successful candidate will serve a critical role and act as the primary point of contact in the communication and coordination among the research team and other members of the Caswell Diabetes Institute to assure the timely implementation and completion of research activities. Responsibilities of the Project Manager will include but are not limited to: establishing and monitoring the progress of project milestones, deliverables and timelines; assist with project budgeting; coordinating team meetings and retreats; communicating with the funding agencies; conducting day-to-day project related operations; taking notes during scientific meetings; performing grant and research administrative tasks; and assisting in writing and submission of progress reports and renewal applications.

The Parker Laboratory is in the Departments of Computational Medicine & Bioinformatics, Human Genetics, and Biostatistics at the University of Michigan. The lab culture is one of openness, scientific rigor, friendliness, and general good humor. For more information, please see the Parker Laboratory website: http://theparkerlab.org

Position: RESEARCH INVESTIGATOR

Location: University of Michigan

Lab: The Welch Laboratory
Position Description:  Research investigator to develop and apply algorithms, machine learning methods, and statistical models for analysis of single-cell genomic data. Our research focuses on enabling biological discovery by applying novel computational approaches to genomic data. Broadly, we seek to understand what genes define the complement of cell types and cell states within healthy tissue, how cells differentiate to their final fates, and how dysregulation of genes within specific cell types contributes to human disease. The lab publishes in high-impact journals, including Cell, Nature, and Nature Biotechnology.

Position: RESEARCH FELLOW  

Location: University of Michigan

Associated Faculty: Castro/Lowenstein, Dept of Neurosurgery

Brief Description: The Castro/Lowenstein Laboratory within the Department of Neurosurgery is accepting applications for a Post-Doctoral Fellowship position funded by NIH.  The successful candidate will join an exciting and productive research team focused on elucidating the molecular and physical basis of brain tumor growth, invasion and the response to novel therapeutics.  The project will study the molecular and cellular mechanisms involved in tumor progression; the role of the extracellular matrix in tumor growth and invasion; the formation and function of oncostreams as described in a recent publication (see below); and the molecular mechanisms which mediate in vivo migration of immune cells into the tumor micro-environment.  The project will also utilize state-of-the-art ?omics? technologies such as Single Cell RNASeq, ChIP-Seq, ATAC-Seq, as well as advanced Bioinformatics. The project has a strong translational component focusing on the development and implementation of novel therapeutic approaches in human clinical trials for brain cancer; these include gene therapy strategies, small molecules, and nano-technologies. The lab is utilizing novel gene therapy and combination therapies and exploring ways to translate the research into novel Phase I clinical trials for GBM.

More information: https://careers.umich.edu/job_detail/238748/postdoctoral-research-fellow

POSTING END DATE 11/26/2023

Position: RESEARCH LAB SPECIALIST SENIOR 

Location: University of Michigan

Lab: Advanced Genomics Core (AGC) 
Position Description: The Biomedical Research Core Facilities Advanced Genomics Core is looking for a skilled research technician to join us full time as a Research Laboratory Specialist Senior. The incumbent will assist in developing, deploying and executing protocols to improve spatial operations in the Advanced Genomics Core.

More information, click button below or visit: https://careers.umich.edu/job_detail/241556/research-lab-specialist-senior-advanced-genomics-core

POSTING END DATE: 11/16/2023

Position: POSTDOCTORAL FELLOW

Location: University of Michigan

Lab: Dr. Sethu Pitchiaya Lab

Brief Description: The laboratory of Dr. Sethu Pitchiaya at the University of Michigan seeks to hire an enthusiastic Postdoctoral fellow to work on exciting projects related to mammalian stress response mechanisms. The Pitchiaya lab is working towards understanding how mammalian cells of various lineages respond to intrinsic and environmental stress and how these programs go awry in degenerative diseases and cancer. To address these pressing questions in physiology and pathology, we probe a variety of in vitro systems, in vivo models and mammalian tissues using an arsenal of contemporary technologies, including single-molecule microscopy, super-resolution imaging, single-cell sequencing and spatial omics.

More information about the lab can be found in https://sethupitchiaya.org/.

More information on the position can be found at: https://careers.umich.edu/job_detail/239537/research-fellow

Position: POSTDOCTORAL FELLOWSHIP IN BRAIN CANCER RESEARCH

Location: University of Michigan

Brief Description: Postdoctoral fellowship in a translational brain tumor research laboratory, Department of Neurosurgery at the University of Michigan Medical School. Using a combination of in vitro and in vivo modeling, analyses of clinical brain tumors samples and multi-omics (including single cell and spatial transcriptomics) our lab focuses on exploring the intrinsic and extrinsic tumor microenvironmental interactions mediating treatment resistance in gliomas. The projects in the laboratory will also have a strong translational component including involvement in an ongoing clinical trial.

More information: https://careers.umich.edu/job_detail/238748/postdoctoral-research-fellow

Position: Research Laboratory Manager

Location: University of Michigan

Brief Description:Department of Internal Medicine Gastroenterology at University of Michigan is looking for a highly-motivated Research Laboratory Manager. Our team studies the mechanisms that lead to obesity, liver disease, and cardiometabolic diseases using human genetics, cell and animal models, and human interventional studies. We are seeking an experienced Research Laboratory Manager with experience managing and helping with both computational as well as wet lab and clinical translational projects.

More information: https://careers.umich.edu/job_detail/234078/research-laboratory-manager

Position: Tenure Track Faculty Positions – Single Cell Spatial Analysis Program (SCSAP)
apply.interfolio.com/127941
Location: Ann Arbor, University of Michigan Medical School

Description: The Single Cell Spatial Analysis Program (SCSAP), as part of the $150 million, campus-wide Biosciences Initiative at the University of Michigan, is soliciting applications for tenure-track faculty positions (all ranks).  The SCSAP is a highly integrative program that provides an intellectual foundation and research resources to enhance single-cell and spatial analyses to the University of Michigan community. For more information, see https://singlecellspatialanalysis.umich.edu.