Biological systems are composed of numerous cell types, intricately organized to form functional tissues and organs. Cell atlas initiatives with single-cell RNA sequencing have begun to characterize cell types based on their RNA expression profiles. However, the tissue organization is lost when cells are dissociated for single-cell sequencing, making it difficult to study how the cellular heterogeneity is contributing to the function of the tissue.
In this presentation, we will introduce you to Vizgen’s all-in-one in situ genomics platform MERSCOPETM which enables the direct profiling of the spatial organization of intact tissue with genomic-scale throughput.
Title: “Perineural Invasion in Oral Cancer: Hitting a Nerve”. Presented by: Nisha D’Silva, BDS, MSD, PhD Donald A Kerr Endowed Collegiate Professor of Oral Pathology, Professor of Dentistry, School of Dentistry and Professor of Pathology University of Michigan
Title: “Integration of single-cell and spatial-seq to gain novel insights into inflammatory skin diseases”. Presented by: Johann E. Gudjonsson, MD, PhD. Arthur C. Curtis Professor of Skin Molecular Immunology and Professor Dermatology, and Taubman Medical Research Institute Scholar, at the University of Michigan.
Title: Accelerating the Next Generation of Immune Medicine with Cellular Proteomics at University of Michigan Single Cell Spatial Analysis Program Presented by : Isoplexis – Brad Annen and Noah Vanderhyde
JOIN US AT THE END OF THE TECH TALK TO LEARN ABOUT AN EXCITING GRANT PROGRAMSPONSORED BY THE UNIVERSITY OF MICHIGAN SINGLE CELL SPATIAL ANALYSIS PROGRAM
Title: Integrative Visualization of Multi-Modal and Spatially-Resolved Single-Cell Data FEATURING: Nils Gehlenborg, PhD Associate Professor of Biomedical Informatics, Harvard Medical School and Director, Master of Biomedical Informatics (MBI) Program
Title: “Morphologic Cell Profiling – from SARS-CoV-2 infection to Liver Organoids” FEATURING: Dr. Jonny Sexton University of Michigan, Department of internal medicine, Division of gastroenterology and hepatology