UNDER CONSTRUCTION – THANK YOU FOR YOUR PATIENCE
Jianping Fu, Ph.D.
Department: Engineering
BIO: Dr. Jianping Fu is a Professor of Mechanical Engineering, Biomedical Engineering, and Cell & Developmental Biology at the University of Michigan. Dr. Fu’s research focuses on stem cell bioengineering, developmental bioengineering, mechanobiology, and microfluidics. Dr. Fu and his co-workers’ research has contributed significantly to the emerging field of “Artificial Embryos”, which was selected by the MIT Technology Review as “10 Breakthrough Technologies of 2018”. Dr. Fu is the recipient of the NSF CAREER Award, the BMES-CMBE Rising Star Award, the ACS Analytical Chemistry Young Innovator Award, the Alexander von Humboldt Foundation Friedrich Wilhelm Bessel Research Award, and numerous awards from the University of Michigan. Dr. Fu is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE), the Royal Society of Chemistry (RSC), the American Society of Mechanical Engineers (ASME), and the International Academy of Medical and Biological Engineers (IAMBE). Dr. Fu was a member of the International Society for Stem Cell Research (ISSCR) Guidelines Working Group (2019-2021), convened to review the oversight process and provide an update to the ISSCR guidelines on in vitro culture of human embryos, creation of stem cell-based embryo models, and in vitrogametogenesis. Dr. Fu currently is a member of the Biomedical Engineering Society Cellular and Molecular Bioengineering Special Interest Group (BMES CMBE-SIG) and the ISSCR Publication Committee. Dr. Fu also serves as the Associate Editor of npj Regenerative Medicine and is an Editorial Board Member of Cell Regeneration, Mechanobiology in Medicine, and Frontiers in Cell and Developmental Biology.
J. Michelle Kahlenberg MD, PhD
J. Michelle Kahlenberg MD, PhD
Department: Internal Medicine and Dermatology
BIO: Dr. J. Michelle Kahlenberg MD, PhD is the Giles G. Boles MD and Dorothy Mulkey MD Research Professor of Rheumatology Associate Professor (soon to be Professor as of 9/1/2023) of Internal Medicine and Dermatology at the University of Michigan. She is the Vice Chair for Basic and Translational Research for the Department of Internal Medicine. Her clinical work is centered on the care of complicated lupus patients, including those with refractory skin disease. Her combines translational approaches using patient samples and murine models to uncover the mechanisms that drive lupus and other autoimmune diseases. In particular, she is focused on unraveling the pathogenic mechanisms in cutaneous lupus, the factors that drive photosensitivity, and how skin inflammation can influence systemic lupus activity. To learn more about her visit:
Xin Luo,Ph.D.
Department: Computational Medicine and Bioinformatics
BIO: My current research direction is about cell-cell communication and single-cell analysis. I will work on single-cell multi-modality integration in the future. Spatial single-cell analysis interests me a lot as spatial-level cell-cell communication has a lot to explore.
Joshua Sodicoff, B.S.E.
Joshua Sodicoff, B.S.E.
Department: Computational Medicine and Bioinformatics
BIO: In my current role, I am developing a methodology for cell type deconvolution of heterogeneous tissue for application to large scale spatial transcriptomic data collected on the murine brain. Determination of the distributions of both well characterized and novel types identified with scRNA-seq data will allow for integration with physiological data and inference on the impact of present fine tissue structures. More generally, I am interested in the spatial organization of biological structure as a manifestation of the emergent properties of small-scale biochemical and genetic interactions with applications in microbial ecology and evolutionary biology.
Mohammad Faisal Syed, Ph.D.
Mohammad Faisal Syed, Ph.D.
Department of Neurosurgery; Department of Cell and Developmental Biology; and Rogel Cancer Center, University of Michigan Medical School
Research Interests: We will use multimodal approaches; single-cell RNA-seq (scRNA-seq), mass cytometry (cytometry time-of-flight (CyTOF) immune phenotyping), and multiplex imaging to discover the spatial phenotypic signatures of the tumor microenvironment in brain tumors.
Yuji Mishina, Ph.D.
Yuji Mishina, Ph.D.
William R. Mann Professor of Dentistry, School of Dentistry
Dr. Mishina’s laboratory is interested in functions of BMP signaling during bone development/remodeling and craniofacial development. Several specific projects include mechanisms of how osteoclasts regulate osteoblast functions in a spatiotemporal manner as a downstream event of BMP signaling, cell fate specification mechanisms in cranial neural crest cells towards chondrogenic lineage, impacts of nanofibrous biomaterials as stem cell niche, identification of crossover points between BMP signaling and mechanosensing for bone homeostasis, and investigation of cellular mechanisms of heterotopic bone formation to identify therapeutic options. We fully utilize genetically modified mouse lines in combination of cellular and molecular approaches including single-cell omics to uncover the above mentioned mechanisms.
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